To deal with the time-consuming problem of calculating the dynamic responses of the bridge under the combined action of random traffic flow and wind，a steel box continuous girder bridge was taken as the engineering background，and the finite element model of the bridge and the vehicle model were established in the commercial software Ansys and SIMPACK，respectively.Then，the dynamic responses of the bridge subjected to the single vehicle load，wind loads，and multiple vehicle loads were calculated to verify the superposability of the dynamic responses of the bridge.On this basis，the Monte Carlo method was used to generate the random traffic flow samples.By using the verified superposability of the dynamic responses of the bridge，the dynamic responses of the bridge under the combined action of random traffic flow and wind were calculated under different random traffic flow conditions，different vehicle speeds，and different wind speeds.The research results show that the superposition method of the dynamic responses of the bridge proposed in this paper can effectively improve the calculation efficiency.The wind load mainly affects the lateral response of the bridge，while the vehicle load mainly affects the vertical response of the bridge.As the traffic flow changes from sparse to dense，the standard deviation values of the vertical displacement and vertical velocity of the main span of the bridge and their increases are larger than those of the side span，while the standard deviation values of the vertical acceleration of the side span and their increases are larger than those of the main span.As the vehicle speed increases，the standard deviation values of the vertical displacement and the vertical velocity of the bridge gradually increase，while those of the vertical acceleration of the side span first increase and then decrease.As the wind speed increases，the standard deviation values of the lateral response of the bridge gradually increase，and the increase of the main span is greater than that of the side span.