The continuous improvement of tunnel construction technology brings a rapid increase in the speed and mileage of tunnel excavation，during which ventilation is a main problem affecting construction efficiency and safety.Taking the Zhuhai Xingye Express （West Line ） tunnel project as an example，this paper studied the influences of forced ventilation，exhaust ventilation，and hybrid ventilation on the dilution and discharge of harmful gas CO near the tunnel face and the wind speed in the tunnel.The results show that hybrid ventilation performs better in CO dilution，while exhaust ventilation has higher CO emission efficiency with a lower wind speed near the working face.Therefore，although forced ventilation is slightly weaker in terms of CO dilution and discharge efficiency，it is still demanded in tunnel construction when maintaining a certain air volume near the working face is considered.