At present，high-strength and high-performance concrete has some disadvantages，such as low flexural strength，large brittleness，and poor volume stability.Reactive powder concrete （RPC ） is a new type of material，which has good mechanical properties and high impermeability.It can reduce the amount of concrete to a greater extent and reduce the weight of the structure，achieving the purpose of safety，reliability，and cost saving.This paper applied RPC to highway prestressed box girder.Through the innovation and optimization of mix ratio，the change in traditional transportation technology，and curing technology research of steam curing shed，it effectively shortens the pouring time of RPC，ensuring the pouring quality and strength.