The short-term water stability of acidic diorite asphalt mixtures with acid-alkaline composite aggregates mixed with cement （2% cement instead of mineral powder ），slaked lime （30% slaked lime water for stone immersion ），and anti-spalling agent （modified asphalt with 0.3% anti-spalling agent ） was evaluated by Marshall test of immersion，freeze-thaw splitting test，and rutting test.Then，by repeated freeze-thaw splitting test，repeated freeze-thaw and baking splitting test，and repeated acid-etching freeze-thaw splitting test，the long-term water stability of the treated acidic diorite asphalt mixtures in different environments was tested.The results show that the physical and mechanical properties of acidic diorite meet the specification requirements；the short-term water stability of the treated acidic diorite asphalt mixtures is significantly improved and meets the specification requirements.However，the long-term water stability of the acidic diorite asphalt mixtures treated with 0.2% anti-spalling agent is poor at high temperatures.The acidic diorite asphalt mixtures treated with 30% slaked lime water have good long-term water stability and can be recommended for engineering applications.